The unexpected success has launched a new round of discussion about a potential cure for HIV.
Gupta, now at Cambridge University, treated the London patient when he was working at University College London.
"We've been trying for many many years to try to figure out how to eradicate those cells or silence the virus within those cells".
The breakthrough comes just days after a patient in London became the second person to be declared HIV free after a bone marrow transplant.
Most experts say the treatment is not suited for everyone living with HIV because of its complexity, the heavy expenses the patient has to shoulder and the risk of dying from the procedures is high.
Now, a separate group of researchers has announced a third instance: the Düsseldorf patient. UNICEF approximates that the region has about 48% of the world's new HIV infections among adults, 55% among children, and 48% of AIDS-related deaths. Walker has tracked such people, dubbed elite controllers, and is starting to figure out how they get infected but remain functionally cured. When HIV-infected individuals are compliant with the prescribed use of the AIDS cocktail, their viral load is undetectable and they become untransmittable, meaning they can not sexually transmit the HIV virus to others.
Brown, who had been living in Berlin, has since moved to the United States and, according to HIV experts, is still HIV-free.
The man who is the subject of the wonderful reversal was treated in the British capital of London.
"They used a reduced intense conditioning regimen but I think that had no influence on the outcome", he said.
After undergoing chemotherapy, he underwent a stem cell transplant in 2016 and also continued with anti-retroviral drugs for 16 months. Unfortunately, the treatment the Berlin and London patients had have failed in other patients, so it is not considered a cure. He believes translation of the approach into gene therapy could work - though it has not yet been proven - and if so, it could become an option for a large number of HIV patients.
The case of the so-called "Dusseldorf patient" was reported at a scientific conference this week, but doctors said their remission is still at an early stage.
Not coincidentally, the stem cells that both patients received in the transplant came from donors with a double set of this rare CCR5 mutation. Those who have two copies of a version of the gene known as CCR5 Delta32 appear to be resistant to HIV infection.
"In the second theory, you are mixing two immune systems, with your new immune system reacting against your original one", Lewin said.
Although it is generally thought that HIV/AIDS cannot be cured, many patients with the virus can live a mostly normal life with anti-viral treatment that keeps the virus at a low level. To treat the lymphoma, the doctors first used drugs to destroy both the lymphoma and also the patient's own bone marrow cells. For now, its use is restricted to those who need the transplant for other reasons, not for HIV alone, said Henrich, who was not involved in the new case study.