Begum was one of a group of schoolgirls from London's Bethnal Green neighbourhood who went to Syria to marry IS fighters in 2015 at a time when the group's online recruitment program lured many impressionable young people to its self-proclaimed caliphate. They weren't fighting anyone.
Mother-of-three Shamima, who gave birth to her third child at the weekend, left east London with two friends in 2015 to join the terrorist group. She needs to be held accountable, as should all jihadis who betrayed their countries by joining those who wished to destroy it.
Ms Begum - who is legally British - has asked for "forgiveness" and "sympathy" as she wants to return to the United Kingdom for the sake of her newborn child.
She said: "I do feel that it's wrong that innocent people did get killed".
"I think a lot of people should have sympathy towards me for everything I've been through", she said in an interview broadcast Sunday.
"If I were advising her, I'd tell her coming back to the United States may be risky for her", former Harvard law professor Alan Dershowitz said. I can't even believe it's even being debated.
"The authorities would probably have to give her a new identity to protect her - then what about the resources of the security services monitoring her to make sure she is not a risk to the British public?"
Now, she and her 18-month-old son are living in the tent-city that is al-Hol - also known as al-Hawl - a refugee camp in northern Syria some 200 miles away from ISIS's "last front" near the village of Baghouz by the Iraqi border.
"My message to both these brides, and any others like them, is this: You made your ISIS husband beds, now you can rot in hell in them".
"During my years in Syria, I would see and experience a way of life and the bad effects of war which changed me", she wrote.
"With each count it could be a 15- to 20-year max, which could run consecutively", he added, referring to her potential prison sentence.
"Everything I've been through, I didn't expect I would go through that".
While declining to discuss Muthana's case specifically, State Department deputy spokesman Robert Palladino said that the status of USA citizens detained in Syria "is by definition extremely complicated". "Losing my children the way I lost them, I don't want to lose this baby as well and this is really not a place to raise children, this camp".
Palladino said that the United States generally did not see a different solution between what to do with USA fighters and with foreigners, saying the fighters pose "a global threat".