As of Sunday morning, Chicago's O'Hare International Airport, a major travel hub, had reported 189 flight cancellations and Midway International Airport had reported an additional 19 canceled flights, according to WGN.
Snowfall was winding down in the Chicago area early Monday, following a blizzard that caused white-out conditions and dumped up to a foot of snow as millions of travelers headed home at the end of the holiday weekend.
Chicago was under a winter storm warning, with 3 to 6 inches of snow and gusty winds forecast.
As of Monday morning, several schools in Kansas, Missouri, Iowa and IL have been forced to close as a result of the snow. Visibility will be severely restricted and travel extremely risky - trees and power lines may be downed with subsequent power outages likely.
"The blizzard warning, which the NWS said was the first in Kansas City since January 31, 2011, stretched south from the Missouri state line to Olathe, west to beyond Topeka and east to Macon, Missouri".
Further south, Gov. Jeff Colyer declared a state of emergency in Kansas on Sunday after 2 to 14 inches (5 to 36 centimeters) of snow fell in parts of the state. Several state and USA highways were impassable in Nebraska, but traffic was moving on Interstate 29 in the southwestern corner of Iowa and Interstate 80 in the eastern part of the state, despite a blanket of snow.
ABC News The winter storm is expected to continue east on Tuesday
The National Weather Service has issued a winter weather advisory beginning at Midnight Sunday 1pm on Monday. It is not out of the possibility that a few locations see greater than 10 inches of snow.
At least two flight out of Hector International Airport are cancelled. The storm also brought risky wind with gusts of up to 80 miles per hour in Colorado and gusts of up to 70 miles per hour in Kansas.
The Illinois Department of Transportation was warning of ice and snow-slicked roads just before rush hour. Flight-tracking website FlightAware reports more than 1,200 flights headed to or from the USA were canceled on one of the busiest travel days of the year.
Drivers whose vehicles become disabled on the tollway can call *999 from a cellphone to get assistance from the Illinois State Police, according to a news release from the agency. Coupled with a gusty northwest wind, power outages and tree damage also are possibilities.
Air Travel in many parts of the U.S.is interrupted Monday morning because of a snowstorm in the Midwest.
Kluber said the storm was expected to hit the Chicago region sometime Sunday evening. This will lead to whiteout conditions, making travel extremely unsafe.