Miller, who was 26, was pronounced dead at his Los Angeles home just before midday yesterday.
The rapper died at the age of 26 after an overdose, according to TMZ, and Chance has already taken to Twitter to heap praise on his good friend, describing Miller as "one of the sweetest guys I ever knew".
On Friday, 7 September it was confirmed that Mac has sadly passed away from an apparent overdose at his home in San Fernando Valley.
Mac also made several references in his music on the subject of drug use and premature death.
Mac Miller began his career as a teenager releasing a series of mixtapes
American rapper Melissa Arnette Elliott said that she is "saddened" and sent "prayers for strength for his family and friends and fans".
According to Variety, the Los Angeles Attorney's Office charged Miller last month for a DUI related to a vehicle accident in the San Fernando Valley.
"I love lean; it's great", he said during the interview. "I wish it started tomorrow". He said, "A lot of times in my life I've put this pressure to hold myself to the standard of whatever I thought I was supposed to be, or how I was supposed to be perceived".
Ariana and Mac seemed inseparable during their romantic relationship that lasted two years. "I'm completely broken. God bless him".
Mac had always been open about his struggles with substance abuse in his music, in particular his largely autobiographical 2014 mixtape, Faces.
Since being forced to disable her comments, many have also voiced their support of the pop star on Twitter, expressing horror at the abuse, misogyny and blame being aimed at Grande, especially in what is very likely a time of deep grieving for the young woman.