An airport source told Fox 5 News that a medical emergency happened on the plane.
Emirates released a Twitter statement confirming the event and revealing that about 10 of the superjumbo jet's passengers had fallen ill.
"Emirates can confirm that about 10 passengers on EK203 from Dubai to NY were taken ill".
"All passengers were screened by the local health authorities prior to disembarkation", it said.
Health officials are taking the remaining passengers off the plane one by one and checking for symptoms, Eric Phillips said in a tweet.
Authorities found 19 people were sickened - 10 of them taken to the hospital, Phillips and the Emirates Airline said.
Images from the airport in NY showed a line of ambulances waiting to check over passengers from the plane. The plane had stopped in Mecca, where there's a flu outbreak, Fox News reported.
The U.S. Centers for Disease Control (CDC) and U.S. Customs and Border Protection were notified of the incident, according to the ABC report.
The New York Police Department's Counterterrorism Bureau said they were monitoring what appears to be a "medical situation" at the airport.
Phillips tweeted at 12:34 p.m. ET that "all the passengers are off and have been evaluated".
"Many of these people should never have been allowed to board".
Passenger Larry Coben, who boarded the plane in Dubai, described the scene on Twitter, as the aircraft landed far from the terminal and was met by dozens of emergency vehicles, lined up and ready to attend to any sick passengers. "Apparently there is over 100 people sick on the bottom floor, so happy I'm up top, it's a double-decker plane 380".
Honig, a former police inspector and commanding officer for JFK and LaGuardia Airports at Port Authority of NY and New Jersey, spoke to CBS2's Mary Calvi about keeping people informed and avoiding panic.
He said that all passengers had their temperature taken as they deplaned.